Emerging Infectious Diseases (Nov 2002)

Global Distribution of Mycobacterium tuberculosis Spoligotypes

  • Ingrid Filliol,
  • Jeffrey R. Driscoll,
  • Dick van Soolingen,
  • Barry N. Kreiswirth,
  • Kristin Kremer,
  • Georges Valétudie,
  • Dang Duc Anh,
  • Rachael Barlow,
  • Dilip Banerjee,
  • Pablo J. Bifani,
  • Karin Brudey,
  • Angel Cataldi,
  • Robert C. Cooksey,
  • Debby V. Cousins,
  • Jeremy W. Dale,
  • Odir A. Dellagostin,
  • Francis Drobniewski,
  • Guido Engelmann,
  • Séverine Ferdinand,
  • Deborah Gascoyne-Binzi,
  • Max Gordon,
  • M. Cristina Gutierrez,
  • Walter H. Haas,
  • Herre Heersma,
  • Gunilla Källenius,
  • Eric Kassa-Kelembho,
  • Tuija Koivula,
  • Ho Minh Ly,
  • Athanasios Makristathis,
  • Caterina Mammina,
  • Gerald Martin,
  • Peter Moström,
  • Igor Mokrousov,
  • Valérie Narbonne,
  • Olga Narvskaya,
  • Antonino Nastasi,
  • Sara Ngo Niobe-Eyangoh,
  • Jean W Pape,
  • Voahangy Rasolofo-Razanamparany,
  • Malin Ridell,
  • M. Lucia Rossetti,
  • Fritz Stauffer,
  • Philip N. Suffys,
  • Howard Takiff,
  • Jeanne Texier-Maugein,
  • Véronique Vincent,
  • Jacobus H. de Waard,
  • Christophe Sola,
  • Nalin Rastogi

DOI
https://doi.org/10.3201/eid0811.020125
Journal volume & issue
Vol. 8, no. 11
pp. 1347 – 1349

Abstract

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We present a short summary of recent observations on the global distribution of the major clades of the Mycobacterium tuberculosis complex, the causative agent of tuberculosis. This global distribution was defined by data-mining of an international spoligotyping database, SpolDB3. This database contains 11,708 patterns from as many clinical isolates originating from more than 90 countries. The 11,708 spoligotypes were clustered into 813 shared types. A total of 1,300 orphan patterns (clinical isolates showing a unique spoligotype) were also detected.

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