The Alteration of Rich Club in Brain Functional Network in Internet Gaming Disorder

QIU Xian-xin; HAN Xu; WANG Yao; DING Wei-na; SUN Ya-wen; ZHOU Yan; LEI Hao; LIN Fu-chun

doi:10.11938/cjmr20212967

Chinese Journal of Magnetic Resonance (Sep 2022)

The Alteration of Rich Club in Brain Functional Network in Internet Gaming Disorder

QIU Xian-xin,
HAN Xu,
WANG Yao,
DING Wei-na,
SUN Ya-wen,
ZHOU Yan,
LEI Hao,
LIN Fu-chun

Affiliations

QIU Xian-xin: 1. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China 2. University of Chinese Academy of Sciences, Beijing 100049, China
HAN Xu: Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
WANG Yao: Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
DING Wei-na: Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
SUN Ya-wen: Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
ZHOU Yan: Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
LEI Hao: 1. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China 2. University of Chinese Academy of Sciences, Beijing 100049, China
LIN Fu-chun: 1. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China 2. University of Chinese Academy of Sciences, Beijing 100049, China

DOI: https://doi.org/10.11938/cjmr20212967
Journal volume & issue: Vol. 39, no. 03
pp. 258 – 266

Abstract

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Internet gaming disorder (IGD) has a great negative impact on teenagers’ study and life. It has been included in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders in 2013. However, the neural mechanism of its effect is yet to be unveiled. In this study, we used resting-state functional magnetic resonance imaging (resting-state fMRI) to explore the differences of rich club structures in the functional brain networks of 30 IGD subjects and 30 age/sex-matched healthy controls. The rich club was found in both IGD subjects and healthy controls, involving important brain regions in default mode, executive control, salience, sensorimotor, auditory and visual networks. IGD subjects had significantly higher rich club connection and higher degree in the right pars orbitalis of inferior frontal gyrus than healthy controls. These findings might suggest that IGD might be more correlated with damage to the rich club connection.

Published in Chinese Journal of Magnetic Resonance

ISSN: 1000-4556 (Print)
Publisher: Science Press
Country of publisher: China
LCC subjects: Science: Physics: Electricity and magnetism
Website: http://121.43.60.238/bpxzz/EN/1000-4556/home.shtml

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