Thrombotic microangiopathy

Abstract

A female patient of 26 years old, with personal pathological history of congenital glaucoma and blindness in the right eye that three days before his admission to “Arnaldo Milian Castro” Hospital began with chills, fever of 39-410°C, universal headache, nausea, projectile vomiting and fetid dark urine, fot those reasons she was admitted in the “Celestino Hernández Robau” Hospital with the presumptive diagnosis of dengue; she evolved bad, so she was sent to “Arnaldo Milian Castro” Hospital with the same symptoms and taking consciousness. On physical examination of the central nervous system, It was appreciated nuchal rigidity ++, bilateral Babinsky, somnolence, disorientation and Glasgow 13/15. An axial computerized tomography was realized that showed hypodense of both thalamuses badly definite, in the midline of both cerebellar hemispheres an image of similar characteristics and III ventricle collapsed. It raised vasculitis with multiple several cerebral infarctions and possible meningoencephalitis and died 26 days admitted. Pathologic findings allowed the diagnosis of damage and multiple organ failure in patient suffering thrombotic microangiopathy.

Keywords

• microangiopatía trombotica
• anemia hemolítica microangiopática