Nature Communications (Feb 2016)
Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase
- Ragnar P. Kristjansson,
- Asmundur Oddsson,
- Hannes Helgason,
- Gardar Sveinbjornsson,
- Gudny A. Arnadottir,
- Brynjar O. Jensson,
- Aslaug Jonasdottir,
- Adalbjorg Jonasdottir,
- G. Bragi Walters,
- Gerald Sulem,
- Arna Oskarsdottir,
- Stefania Benonisdottir,
- Olafur B. Davidsson,
- Gisli Masson,
- Olafur Th Magnusson,
- Hilma Holm,
- Olof Sigurdardottir,
- Ingileif Jonsdottir,
- Gudmundur I. Eyjolfsson,
- Isleifur Olafsson,
- Daniel F. Gudbjartsson,
- Unnur Thorsteinsdottir,
- Patrick Sulem,
- Kari Stefansson
Affiliations
- Ragnar P. Kristjansson
- deCODE genetics/Amgen, Inc.
- Asmundur Oddsson
- deCODE genetics/Amgen, Inc.
- Hannes Helgason
- deCODE genetics/Amgen, Inc.
- Gardar Sveinbjornsson
- deCODE genetics/Amgen, Inc.
- Gudny A. Arnadottir
- deCODE genetics/Amgen, Inc.
- Brynjar O. Jensson
- deCODE genetics/Amgen, Inc.
- Aslaug Jonasdottir
- deCODE genetics/Amgen, Inc.
- Adalbjorg Jonasdottir
- deCODE genetics/Amgen, Inc.
- G. Bragi Walters
- deCODE genetics/Amgen, Inc.
- Gerald Sulem
- deCODE genetics/Amgen, Inc.
- Arna Oskarsdottir
- deCODE genetics/Amgen, Inc.
- Stefania Benonisdottir
- deCODE genetics/Amgen, Inc.
- Olafur B. Davidsson
- deCODE genetics/Amgen, Inc.
- Gisli Masson
- deCODE genetics/Amgen, Inc.
- Olafur Th Magnusson
- deCODE genetics/Amgen, Inc.
- Hilma Holm
- deCODE genetics/Amgen, Inc.
- Olof Sigurdardottir
- Department of Clinical Biochemistry, Akureyri Hospital
- Ingileif Jonsdottir
- deCODE genetics/Amgen, Inc.
- Gudmundur I. Eyjolfsson
- Icelandic Medical Center (Laeknasetrid), Laboratory in Mjodd (RAM)
- Isleifur Olafsson
- Department of Clinical Biochemistry, Landspitali University Hospital
- Daniel F. Gudbjartsson
- deCODE genetics/Amgen, Inc.
- Unnur Thorsteinsdottir
- deCODE genetics/Amgen, Inc.
- Patrick Sulem
- deCODE genetics/Amgen, Inc.
- Kari Stefansson
- deCODE genetics/Amgen, Inc.
- DOI
- https://doi.org/10.1038/ncomms10572
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 8
Abstract
Creatine kinase (CK) and lactate dehydrogenase (LDH) are biomarkers of tissue damages including myopathy and myocardial infarction. Here, Patrick Sulem and colleagues perform a genome-wide association study to identify common and rare genetic variants that associates with serum CK or LDH levels.
