Nature Communications (Sep 2018)

Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system

  • Charles Petitpré,
  • Haohao Wu,
  • Anil Sharma,
  • Anna Tokarska,
  • Paula Fontanet,
  • Yiqiao Wang,
  • Françoise Helmbacher,
  • Kevin Yackle,
  • Gilad Silberberg,
  • Saida Hadjab,
  • François Lallemend

DOI
https://doi.org/10.1038/s41467-018-06033-3
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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Spiral ganglion neurons (SGNs) of the cochlea receive input from hair cells and project to the auditory brainstem. Here, the authors perform single-cell RNA sequencing to identify four SGN subclasses and characterize their molecular profile, electrophysiological properties and connectivity.