Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H

Cong Zeng; John P. Evans; Julia N. Faraone; Panke Qu; Yi-Min Zheng; Linda Saif; Eugene M. Oltz; Gerard Lozanski; Richard J. Gumina; Shan-Lu Liu

doi:10.1128/mBio.02510-21

mBio (Oct 2021)

Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H

Cong Zeng,
John P. Evans,
Julia N. Faraone,
Panke Qu,
Yi-Min Zheng,
Linda Saif,
Eugene M. Oltz,
Gerard Lozanski,
Richard J. Gumina,
Shan-Lu Liu

Affiliations

Cong Zeng: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA
John P. Evans: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA
Julia N. Faraone: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA
Panke Qu: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA
Yi-Min Zheng: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA
Linda Saif: ORCiD; Center for Food Animal Health, Animal Sciences Department, OARDC, College of Food, Agricultural and Environmental Sciences and Veterinary Preventive Medicine Department, College of Veterinary Medicine, The Ohio State University, Wooster, Ohio, USA
Eugene M. Oltz: Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA
Gerard Lozanski: Department of Pathology, The Ohio State University, Columbus, Ohio, USA
Richard J. Gumina: Division of Cardiovascular Medicine, Department of Internal Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA
Shan-Lu Liu: Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA

DOI: https://doi.org/10.1128/mBio.02510-21
Journal volume & issue: Vol. 12, no. 5

Abstract

Read online

SARS-CoV-2, the causative agent of COVID-19, is rapidly evolving to be more transmissible and to evade acquired immunity. To date, most investigations of SARS-CoV-2 variants have focused on RBD mutations.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal