Antibacterial and Antioxidant Properties of Scrophularia Striata Boiss. Methanolic Extract

Abstract

Scrophularia striata belongs to the Scrophulariaceae family and widely grows in the several regions throughout the world especially Iran, Turkey and Azerbaijan. The aims of the present study were to evaluate antibacterial activity of the S. striata methanolic extract collected from west part of Iran by micro-broth dilution and agar disk diffusion assays, and also determine its antioxidant properties using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and thiobarbituric acid (TBA) methods. The most antibacterial activity was observed against Bacillus cereus, followed by B. subtilis, S. aureus. Listeria monocytogenes, Salmonella typhimurium and Escherichia coli O157:H7, respectively. Moreover, the scavenging properties on DPPH radical scavenging and TBA of S. striata methanolic extract were found to be 0.92 ± 0.21 and 7.98 ± 0.23, respectively. The strong in vitro antibacterial and antioxidant activities of S. striata methanolic extract supports its traditional application in the treatments and/or prevention of different diseases.

Keywords

• scrophularia striata; antibacterial; antioxidant; iran.