Trends in Incidence of Urinary Tract Infection in Mainland China from 1990 to 2019

Abstract

Sheng Yuan,1,2 Ying Shi,3 Minmin Li,4 Xiaojun Hu,5 Ruhai Bai6 1Department of New Medicine and Needle Pricking, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China; 3School of Public Health, Shaanxi University of Chinese Medicine, Xi’an, Shaanxi, People’s Republic of China; 4Department of Infection Disease Control and Prevention, Shaanxi Provincial Center for Disease Control and Prevention, Xi’an, Shaanxi, People’s Republic of China; 5Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 6School of Public Affair, Nanjing University of Science and Technology, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Ruhai BaiSchool of Public Affair, Nanjing University of Science and Technology, No. 200, Xiao Lingwei Street, Nanjing, Jiangsu, People’s Republic of ChinaEmail [email protected]: Urinary tract infection (UTI) is the second-most-common type of infection in China. This study aimed to determine the long-term trends in the incidence of UTI in Mainland China between 1990 and 2019.Materials and Methods: Data were extracted from the Global Burden of Disease Study 2019 and were analyzed with the age–period–cohort framework.Results: The net drift in the incidence of UTI was – 0.37% (95% CI: – 0.40%, – 0.35%) in males and – 0.25% (95% CI: – 0.29%, – 0.20%) in females. For males, the local drift was lower than 0 (P< 0.05) among those younger than 90 years. For females, the local drift was lower than 0 (P< 0.05) among those younger than 60 years and higher than 0 (P< 0.05) in those aged 65– 79 years. In the same birth cohort, the incidence of UTI was higher in females than in males in all age groups (P< 0.05). The period relative risk (RR) showed a decreasing pattern after 2005 in both sexes. The cohort RR showed a downward trend of the birth cohort after 1905 for males and 1960 for females.Conclusion: The incidence has increased significantly among older females over the past 30 years. It is necessary to develop a comprehensive intervention plan for reproductive health services covering females and males of all ages.Keywords: age–period–cohort analysis, urinary tract infection, bacterial infection

Keywords

• age–period–cohort analysis
• urinary tract infection
• bacterial infection