Nature Communications (Mar 2022)

Assessment of global health risk of antibiotic resistance genes

  • Zhenyan Zhang,
  • Qi Zhang,
  • Tingzhang Wang,
  • Nuohan Xu,
  • Tao Lu,
  • Wenjie Hong,
  • Josep Penuelas,
  • Michael Gillings,
  • Meixia Wang,
  • Wenwen Gao,
  • Haifeng Qian

DOI
https://doi.org/10.1038/s41467-022-29283-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health. Here, Zhang et al. analyze 4572 metagenomic samples to illustrate the global patterns of ARG distribution in diverse habitats. They quantitatively evaluate the health risk to humans of 2561 ARGs by integrating human accessibility, mobility, pathogenicity and clinical availability. With the machine learning, they map the antibiotic resistance threats in global marine habitats.