Emerging Infectious Diseases (May 2018)
External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil
- Carlo Fischer,
- Celia Pedroso,
- Alfredo Mendrone,
- Ana Maria Bispo de Filippis,
- Antonio Carlos Rosário Vallinoto,
- Bergmann Morais Ribeiro,
- Edison Luiz Durigon,
- Ernesto T.A. Marques,
- Gubio S. Campos,
- Isabelle F.T. Viana,
- José Eduardo Levi,
- Luciano Cesar Scarpelli,
- Mauricio Lacerda Nogueira,
- Michele de Souza Bastos,
- Nathalia C. Santiago Souza,
- Ricardo Khouri,
- Sanny M. Costa Lira,
- Shirley Vasconcelos Komninakis,
- Cécile Baronti,
- Rémi N. Charrel,
- Beate M. Kümmerer,
- Christian Drosten,
- Carlos Brites,
- Xavier de Lamballerie,
- Matthias Niedrig,
- Eduardo Martins Netto,
- Jan Felix Drexler
Affiliations
- Carlo Fischer
- Celia Pedroso
- Alfredo Mendrone
- Ana Maria Bispo de Filippis
- Antonio Carlos Rosário Vallinoto
- Bergmann Morais Ribeiro
- Edison Luiz Durigon
- Ernesto T.A. Marques
- Gubio S. Campos
- Isabelle F.T. Viana
- José Eduardo Levi
- Luciano Cesar Scarpelli
- Mauricio Lacerda Nogueira
- Michele de Souza Bastos
- Nathalia C. Santiago Souza
- Ricardo Khouri
- Sanny M. Costa Lira
- Shirley Vasconcelos Komninakis
- Cécile Baronti
- Rémi N. Charrel
- Beate M. Kümmerer
- Christian Drosten
- Carlos Brites
- Xavier de Lamballerie
- Matthias Niedrig
- Eduardo Martins Netto
- Jan Felix Drexler
- DOI
- https://doi.org/10.3201/eid2405.171747
- Journal volume & issue
-
Vol. 24,
no. 5
pp. 888 – 892
Abstract
We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimates of Zika virus–associated disease and determination of patient care.
Keywords
