Multiple brain metastases in a patient with ypT0N0 micropapillary urothelial carcinoma of the bladder

Abstract

Radical cystectomy (RC) after neoadjuvant chemotherapy (NAC) is the gold standard for management of muscle-invasive bladder cancer (MIBC). Patients without residual tumor at the time of extirpative surgery (ypT0) have excellent prognosis. Distant metastases in this population are rare. We present a unique case of a patient with ypT0N0 urothelial carcinoma (UC) with rapid development of metastasis to the brain.

Keywords

• Muscle invasive bladder cancer
• Neoadjuvant chemotherapy
• Brain metastass