Vaccines (Aug 2022)
Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis
- Jonny Karunia Fajar,
- Malik Sallam,
- Gatot Soegiarto,
- Yani Jane Sugiri,
- Muhammad Anshory,
- Laksmi Wulandari,
- Stephanie Astrid Puspitasari Kosasih,
- Muhammad Ilmawan,
- Kusnaeni Kusnaeni,
- Muhammad Fikri,
- Frilianty Putri,
- Baitul Hamdi,
- Izza Dinalhaque Pranatasari,
- Lily Aina,
- Lailatul Maghfiroh,
- Fernanda Septi Ikhriandanti,
- Wa Ode Endiaverni,
- Krisna Wahyu Nugraha,
- Ory Wiranudirja,
- Sally Edinov,
- Ujang Hamdani,
- Lathifatul Rosyidah,
- Hanny Lubaba,
- Rinto Ariwibowo,
- Riska Andistyani,
- Ria Fitriani,
- Miftahul Hasanah,
- Fardha Ad Durrun Nafis,
- Fredo Tamara,
- Fitri Olga Latamu,
- Hendrix Indra Kusuma,
- Ali A. Rabaan,
- Saad Alhumaid,
- Abbas Al Mutair,
- Mohammed Garout,
- Muhammad A. Halwani,
- Mubarak Alfaresi,
- Reyouf Al Azmi,
- Nada A. Alasiri,
- Abeer N. Alshukairi,
- Kuldeep Dhama,
- Harapan Harapan
Affiliations
- Jonny Karunia Fajar
- Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Malik Sallam
- Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan
- Gatot Soegiarto
- Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya 60286, Indonesia
- Yani Jane Sugiri
- Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Muhammad Anshory
- Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Laksmi Wulandari
- Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya 60286, Indonesia
- Stephanie Astrid Puspitasari Kosasih
- Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Muhammad Ilmawan
- Department of Urology, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Kusnaeni Kusnaeni
- Faculty of Matematics and Sciences, Institut Pertanian Bogor, Bogor 16680, Indonesia
- Muhammad Fikri
- Faculty of Matematics and Sciences, Institut Pertanian Bogor, Bogor 16680, Indonesia
- Frilianty Putri
- School of Veterinary Medicine and Biomedicine, Institut Pertanian Bogor, Bogor 16680, Indonesia
- Baitul Hamdi
- Faculty of Economy and Business, Universitas Airlangga, Surabaya 60286, Indonesia
- Izza Dinalhaque Pranatasari
- Faculty of Public Health, Universitas Airlangga, Surabaya 60286, Indonesia
- Lily Aina
- Faculty of Pharmacy, Universitas Airlangga, Surabaya 60286, Indonesia
- Lailatul Maghfiroh
- Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya 60286, Indonesia
- Fernanda Septi Ikhriandanti
- Faculty of Medicine, Universitas Airlangga, Surabaya 60286, Indonesia
- Wa Ode Endiaverni
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Krisna Wahyu Nugraha
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Ory Wiranudirja
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Sally Edinov
- Faculty of Economics and Business, Riau University, Pekanbaru 28293, Indonesia
- Ujang Hamdani
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Lathifatul Rosyidah
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Hanny Lubaba
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Rinto Ariwibowo
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Riska Andistyani
- Faculty of Economy and Business, Universitas Brawijaya, Malang 65145, Indonesia
- Ria Fitriani
- Faculty of Administrative Science, Universitas Brawijaya, Malang 65145, Indonesia
- Miftahul Hasanah
- Faculty of Animal Science, Universitas Brawijaya, Malang 65145, Indonesia
- Fardha Ad Durrun Nafis
- Faculty of Animal Science, Universitas Brawijaya, Malang 65145, Indonesia
- Fredo Tamara
- Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Fitri Olga Latamu
- Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia
- Hendrix Indra Kusuma
- Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
- Ali A. Rabaan
- Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia
- Saad Alhumaid
- Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa 31982, Saudi Arabia
- Abbas Al Mutair
- Research Center, Almoosa Specialist Hospital, Al Mubarrazs 36342, Saudi Arabia
- Mohammed Garout
- Department of Community Medicine and Health Care for Pilgrims, Faculty of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia
- Muhammad A. Halwani
- Department of Medical Microbiology, Faculty of Medicine, Al Baha University, Al Baha 4781, Saudi Arabia
- Mubarak Alfaresi
- Department of Pathology and Laboratory Medicine, Sheikh Khalifa General Hospital, Umm Al Quwain 499, United Arab Emirates
- Reyouf Al Azmi
- Infection Prevention and Control, Eastern Health Cluster, Dammam 32253, Saudi Arabia
- Nada A. Alasiri
- Scientific Advisory Council, InsanCare Group for Scientific Studies and Specialized Business Solutions, Riyadh 13313, Saudi Arabia
- Abeer N. Alshukairi
- College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia
- Kuldeep Dhama
- Division of Pathology, ICAR–Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, India
- Harapan Harapan
- Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
- DOI
- https://doi.org/10.3390/vaccines10081356
- Journal volume & issue
-
Vol. 10,
no. 8
p. 1356
Abstract
Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.
Keywords
