Nature Communications (Jan 2022)

Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer

  • Nikita Sushentsev,
  • Mary A. McLean,
  • Anne Y. Warren,
  • Arnold J. V. Benjamin,
  • Cara Brodie,
  • Amy Frary,
  • Andrew B. Gill,
  • Julia Jones,
  • Joshua D. Kaggie,
  • Benjamin W. Lamb,
  • Matthew J. Locke,
  • Jodi L. Miller,
  • Ian G. Mills,
  • Andrew N. Priest,
  • Fraser J. L. Robb,
  • Nimish Shah,
  • Rolf S. Schulte,
  • Martin J. Graves,
  • Vincent J. Gnanapragasam,
  • Kevin M. Brindle,
  • Tristan Barrett,
  • Ferdia A. Gallagher

DOI
https://doi.org/10.1038/s41467-022-28069-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

Read online

Your paper will be accompanied by the following editor’s summary. Please let us know if there are any inaccuracies: ‘Hyperpolarised ¹³C-MRI is used to image cancer metabolism. Here the authors use this technique in prostate cancer and show that it can differentiate distinct disease states.