Nature Communications (Jan 2022)
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer
- Nikita Sushentsev,
- Mary A. McLean,
- Anne Y. Warren,
- Arnold J. V. Benjamin,
- Cara Brodie,
- Amy Frary,
- Andrew B. Gill,
- Julia Jones,
- Joshua D. Kaggie,
- Benjamin W. Lamb,
- Matthew J. Locke,
- Jodi L. Miller,
- Ian G. Mills,
- Andrew N. Priest,
- Fraser J. L. Robb,
- Nimish Shah,
- Rolf S. Schulte,
- Martin J. Graves,
- Vincent J. Gnanapragasam,
- Kevin M. Brindle,
- Tristan Barrett,
- Ferdia A. Gallagher
Affiliations
- Nikita Sushentsev
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Mary A. McLean
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Anne Y. Warren
- Department of Pathology, Cambridge University Hospitals NHS Foundation Trust
- Arnold J. V. Benjamin
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Cara Brodie
- Cancer Research UK Cambridge Institute, University of Cambridge
- Amy Frary
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Andrew B. Gill
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Julia Jones
- Cancer Research UK Cambridge Institute, University of Cambridge
- Joshua D. Kaggie
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Benjamin W. Lamb
- Department of Urology, Cambridge University Hospitals NHS Foundation Trust
- Matthew J. Locke
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Jodi L. Miller
- Cancer Research UK Cambridge Institute, University of Cambridge
- Ian G. Mills
- Patrick G Johnston Centre for Cancer Research, Queen’s University Belfast
- Andrew N. Priest
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Fraser J. L. Robb
- GE Healthcare
- Nimish Shah
- Department of Urology, Cambridge University Hospitals NHS Foundation Trust
- Rolf S. Schulte
- GE Healthcare
- Martin J. Graves
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Vincent J. Gnanapragasam
- Department of Urology, Cambridge University Hospitals NHS Foundation Trust
- Kevin M. Brindle
- Cancer Research UK Cambridge Institute, University of Cambridge
- Tristan Barrett
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- Ferdia A. Gallagher
- Department of Radiology, Addenbrooke’s Hospital and University of Cambridge
- DOI
- https://doi.org/10.1038/s41467-022-28069-2
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
Your paper will be accompanied by the following editor’s summary. Please let us know if there are any inaccuracies: ‘Hyperpolarised ¹³C-MRI is used to image cancer metabolism. Here the authors use this technique in prostate cancer and show that it can differentiate distinct disease states.