Stromal gastrointestinal tumor of ileum (clinical case)

Abstract

A small intestine malignant tumor reaches 2,1% in the structure of digestive tract neoplasms. This type of disease presented as duodenal (about 50%), jejunum (30%) and ileum (20%) malignant tumors. These non-epithelial lesions are stromal gastrointestinal tumors (GIST) and recently distinguished as an independent nosological unit, which has individual histological, immunohistochemical and molecular-genetic signs. Diagnostic confirmation of GIST is the measurement of c-Kit expression (CD-117) by immunohistochemistry. The main methods of GIST treatment is surgery and chemotherapy. Our report proves once again, that the diagnosis of small bowel tumor is extremely difficult. We operated a patient with 4th stage of the malignant disease. However, using such a simple method as an ultrasound has allowed to suspect abnormalities in the small intestine. Abdominal CT was performed after that. The key to successful treatment is the use of modern diagnostic methods - transrectal endosonography of pelvis and capsule endoscopy of the small intestine, that allows to diagnose correctly. The main method of treatment is removing of the GIST tumor with lymph node dissection and chemotherapy (Imatinib).

Keywords

• рак тонкой кишки
• гастроинтестинальная стромальная опухоль тонкой кишки
• срединная лапаро-томия
• химиотерапия
• small intestine malignant tumor
• stromal gastrointestinal tumor
• midline laparotomy
• chemotherapy