Single‐cell sequencing reveals alterations in the peripheral blood mononuclear cell landscape and monocyte status during colorectal adenocarcinoma formation

• Jiasheng Xu,
• Yeting Hu,
• Jie Zhao,
• Xiangxing Kong,
• Sijian Xia,
• Siqi Dai,
• Lei Ding,
• Tongtong Bu,
• Yue Cao,
• Manjiao Liu,
• Linlin Yan,
• Qian Xiao,
• Hao Guo,
• Ying Yuan,
• Dong Xu,
• Kefeng Ding

Affiliations

Jiasheng Xu

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Yeting Hu

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Jie Zhao

The State Key Laboratory of Neurology and Oncology Drug Development Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd. Nanjing China

Xiangxing Kong

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Sijian Xia

The State Key Laboratory of Neurology and Oncology Drug Development Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd. Nanjing China

Siqi Dai

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Lei Ding

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Tongtong Bu

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Yue Cao

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Manjiao Liu

The State Key Laboratory of Neurology and Oncology Drug Development Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd. Nanjing China

Linlin Yan

The State Key Laboratory of Neurology and Oncology Drug Development Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd. Nanjing China

Qian Xiao

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Hao Guo

The State Key Laboratory of Neurology and Oncology Drug Development Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd. Nanjing China

Ying Yuan

The Department of Medical Oncology the Second Affiliated Hospital of Zhejiang University Hangzhou China

Dong Xu

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China

Kefeng Ding

Department of Colorectal Surgery The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology) Zhejiang University Hangzhou China