Gynecologic Oncology Reports (Dec 2022)

Stage and outcomes of invasive cervical cancer patients in Botswana: A prospective cohort study from 2013 to 2020

  • Surbhi Grover,
  • Jessica George,
  • Shawna Tuli,
  • Katie Lichter,
  • Rohini Bhatia,
  • Barati Monare,
  • Ganen Chinniah,
  • Lisa Bazzett-Matabele,
  • Memory Bvochora-Nsingo,
  • Sebathu Chiyapo,
  • Dawn Balang,
  • Tlotlo Ralefala,
  • Peter Vuylsteke,
  • Rebecca Luckett,
  • Sanghyuk Shin,
  • Nicola Zetola,
  • Doreen Ramogola-Masire

Journal volume & issue
Vol. 44
p. 101094

Abstract

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Objective: To present the stage distribution, patterns of care, and outcomes of patients from Botswana with invasive cervical cancer, living with or without HIV. Methods: Between 2013 and 2020, women with cervical cancer were prospectively enrolled in an observational cohort study. Results: A total of 1,043 patients were enrolled; 69% were women living with HIV. The median age of the cohort was 47 years (interquartile range [IQR] 40–58 years), with women living with HIV presenting at a younger age compared to women without HIV (44 versus 61 years, p 10 g/dL (HR 0.51, p < 0.001) compared to Hb ≤ 10 g/dL. Conclusions: Among women in Botswana with cervical cancer, most patients presented with stage II or III disease warranting radiation therapy or chemoradiation. While two-thirds of cervical cancer patients were women living with HIV, HIV did not impact OS.

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