Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled to quadrupole-time-of-flight-mass-spectrometry

Affiliations

Kai On Chu: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, China
Kai On Chu: Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, China
Gene Chi Wai Man: Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, China
Sze Wan Hung: Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, China
Tak Hang Chan: Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
Tak Hang Chan: Department of Chemistry, McGill University, Montreal, QC, Canada
Wai Yip Thomas Lee: Aptorum Group Limited, Hong Kong, China
Kwok Ping Chan: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, China
Chi Pui Pang: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, China
Chi Pui Pang: Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, China
Chi Chiu Wang: Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, China
Chi Chiu Wang: Li Ka Shing Institute of Health Sciences; and School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, China

Abstract

Graphical Abstract