Transcatheter Heart Valve Thrombosis in a Patient With Polycythemia Vera Despite Apixaban Therapy for Atrial Fibrillation

Gauranga Mahalwar, MD; Nicole Lao, MD; Arslan Babar, MD; Samir R. Kapadia, MD; Ankur Kalra, MD; David Cutler, MD; Per Wierup, MD

JACC: Case Reports (Feb 2021)

Transcatheter Heart Valve Thrombosis in a Patient With Polycythemia Vera Despite Apixaban Therapy for Atrial Fibrillation

Gauranga Mahalwar, MD,
Nicole Lao, MD,
Arslan Babar, MD,
Samir R. Kapadia, MD,
Ankur Kalra, MD,
David Cutler, MD,
Per Wierup, MD

Affiliations

Gauranga Mahalwar, MD: Department of Internal Medicine, Cleveland Clinic Akron General, Akron, Ohio, USA
Nicole Lao, MD: Department of Internal Medicine, Cleveland Clinic Akron General, Akron, Ohio, USA
Arslan Babar, MD: Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA
Samir R. Kapadia, MD: Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA
Ankur Kalra, MD: Department of Internal Medicine, Cleveland Clinic Akron General, Akron, Ohio, USA; Heart, Vascular and Thoracic Department, Cleveland Clinic Akron General, Akron, Ohio, USA; Address for correspondence: Dr. Ankur Kalra, Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 224 West Exchange Street, Suite 225, Akron, Ohio 44302, USA.
David Cutler, MD: Heart, Vascular and Thoracic Department, Cleveland Clinic Akron General, Akron, Ohio, USA
Per Wierup, MD: Department of Thoracic and Cardiovascular Surgery, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA

Journal volume & issue: Vol. 3, no. 2
pp. 269 – 272

Abstract

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We present a case of transcatheter heart valve thrombosis in a 76-year-old man with paroxysmal atrial fibrillation on therapeutic anticoagulation with apixaban and polycythemia vera. The incidence of transcatheter heart valve thrombosis in patients with atrial fibrillation and on adequate anticoagulation is not well reported. (Level of Difficulty: Intermediate.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

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