GENETICS OF AUTISTIC DISORDER (REVIEW OF FOREIGN LITERATURE)

Abstract

Autism can occur in combination with chromosomal and genetic syndromes, malformations of the brain, metabolic diseases, etc. In this regard, currently adopted the term «atypical» or «syndromic» autism – autism, which is a symptom of another disease. Genetic and chromosomal causes account for 25-50% of cases of autism. The authors presented a detailed review of the literature devoted to the genetic aspects of autism. The article discusses known hereditary diseases, manifested as autistic disorder, classification of genes-candidates of autism, the theory of autism pathogenesis, approaches to the diagnosis, as well as the problems associated with genetic counseling for patients with autism.

Keywords

• autistic disorder
• etiology
• pathogenesis
• genetic diseases
• genetic counseling