Biomolecular condensates as arbiters of biochemical reactions inside the nucleus

Guillaume Laflamme; Karim Mekhail

doi:10.1038/s42003-020-01517-9

Communications Biology (Dec 2020)

Biomolecular condensates as arbiters of biochemical reactions inside the nucleus

Guillaume Laflamme,
Karim Mekhail

Affiliations

Guillaume Laflamme: Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, MaRS Centre West Tower, 661 University Avenue, M5G 1M1
Karim Mekhail: Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, MaRS Centre West Tower, 661 University Avenue, M5G 1M1

DOI: https://doi.org/10.1038/s42003-020-01517-9
Journal volume & issue: Vol. 3, no. 1
pp. 1 – 8

Abstract

Read online

Laflamme and Mekhail discuss emerging nuclear roles for LLPS in genome organization, gene expression and DNA repair, highlighting the emerging notion that biomolecular condensates regulate the sequential engagement of molecules in multistep biological processes.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal