Clinical Implementation of a 6D Treatment Chair for Fixed Ion Beam Lines

Jiayao Sun; Jiayao Sun; Jiayao Sun; Lin Kong; Lin Kong; Lin Kong; Zhi Chen; Zhi Chen; Zhi Chen; Dan You; Dan You; Dan You; Jingfang Mao; Jingfang Mao; Jingfang Mao; Xiyin Guan; Xiyin Guan; Xiyin Guan; Xiaodong Wu; Xiaodong Wu; Xiaodong Wu; Yinxiangzi Sheng; Yinxiangzi Sheng; Yinxiangzi Sheng

doi:10.3389/fonc.2021.694749

Frontiers in Oncology (Jun 2021)

Clinical Implementation of a 6D Treatment Chair for Fixed Ion Beam Lines

Jiayao Sun,
Jiayao Sun,
Jiayao Sun,
Lin Kong,
Lin Kong,
Lin Kong,
Zhi Chen,
Zhi Chen,
Zhi Chen,
Dan You,
Dan You,
Dan You,
Jingfang Mao,
Jingfang Mao,
Jingfang Mao,
Xiyin Guan,
Xiyin Guan,
Xiyin Guan,
Xiaodong Wu,
Xiaodong Wu,
Xiaodong Wu,
Yinxiangzi Sheng,
Yinxiangzi Sheng,
Yinxiangzi Sheng

Affiliations

Jiayao Sun: Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China
Jiayao Sun: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Jiayao Sun: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Lin Kong: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Lin Kong: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Lin Kong: Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China
Zhi Chen: Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China
Zhi Chen: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Zhi Chen: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Dan You: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Dan You: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Dan You: Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China
Jingfang Mao: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Jingfang Mao: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Jingfang Mao: Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China
Xiyin Guan: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Xiyin Guan: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Xiyin Guan: Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China
Xiaodong Wu: Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China
Xiaodong Wu: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Xiaodong Wu: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China
Yinxiangzi Sheng: Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China
Yinxiangzi Sheng: Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China
Yinxiangzi Sheng: Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China

DOI: https://doi.org/10.3389/fonc.2021.694749
Journal volume & issue: Vol. 11

Abstract

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PurposeTo verify the practicality and safety of a treatment chair with six degrees of freedom (6DTC) through demonstrating the efficacy of the workflow in clinical settings and analyzing the obtained technical data, including intra-fraction patient movement during the use of the 6DTC.Materials and MethodsA clinical study was designed and conducted to test the clinical treatment workflow and the safety of the 6DTC. Based on the demonstrated dosimetric advantages, fifteen patients with head and neck tumors were selected and treated with the 6DTC. The positional error at the first beam position (PE-B1) and the second beam position (PE-B2) were analyzed and compared with the results from daily quality assurance (QA) procedures of the 6DTC and imaging system performed each day before clinical treatment. The intra-fraction patient movement was derived from the total patient alignment positional error and the QA data based on a Gaussian distribution formulism.ResultsThe QA results showed sub-millimeter mechanical accuracy of the 6DTC over the course of the clinical study. For 150 patient treatment fractions, the mean deviations between PE-B1 and PE-B2 were 0.13mm (SD 0.88mm), 0.25mm (SD 1.17mm), -0.57mm (SD 0.85mm), 0.02° (SD 0.35°), 0.00° (SD 0.37°), and -0.02° (SD 0.37°) in the x, y, z (translational), and u, v, w (rotational) directions, respectively. The calculated intra-fraction patient movement was -0.08mm (SD 0.56mm), 0.71mm (SD 1.12mm), -0.52mm (SD 0.84mm), 0.10° (SD 0.32°), 0.09° (SD 0.36°), and -0.04° (SD 0.36°) in the x, y, z, u, v, w directions, respectively.ConclusionsThe performance stability of the 6DTC was satisfactory. The position accuracy and intra-fraction patient movement in an upright posture with the 6DTC were verified and found adequate for clinical implementation.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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