Annals of Coloproctology (Aug 2024)
The Italian Unitary Society of Colon-Proctology (Società Italiana Unitaria di Colonproctologia) guidelines for the management of acute and chronic hemorrhoidal disease
- Antonio Brillantino,
- Adolfo Renzi,
- Pasquale Talento,
- Luigi Brusciano,
- Luigi Marano,
- Maurizio Grillo,
- Mauro Natale Maglio,
- Fabrizio Foroni,
- Alessio Palumbo,
- Maria Laura Sandoval Sotelo,
- Luciano Vicenzo,
- Michele Lanza,
- Giovanna Frezza,
- Massimo Antropoli,
- Claudio Gambardella,
- Luigi Monaco,
- Ilaria Ferrante,
- Domenico Izzo,
- Alfredo Giordano,
- Michele Pinto,
- Corrado Fantini,
- Marcello Gasparrini,
- Michele Schiano Di Visconte,
- Francesca Milazzo,
- Giovanni Ferreri,
- Andrea Braini,
- Umberto Cocozza,
- Massimo Pezzatini,
- Valeria Gianfreda,
- Alberto Di Leo,
- Vincenzo Landolfi,
- Umberto Favetta,
- Sergio Agradi,
- Giovanni Marino,
- Massimiliano Varriale,
- Massimo Mongardini,
- Claudio Eduardo Fernando Antonio Pagano,
- Riccardo Brachet Contul,
- Nando Gallese,
- Giampiero Ucchino,
- Michele D’Ambra,
- Roberto Rizzato,
- Giacomo Sarzo,
- Bruno Masci,
- Francesca Da Pozzo,
- Simona Ascanelli,
- Patrizia Liguori,
- Angela Pezzolla,
- Francesca Iacobellis,
- Erika Boriani,
- Eugenio Cudazzo,
- Francesca Babic,
- Carmelo Geremia,
- Alessandro Bussotti,
- Mario Cicconi,
- Antonia Di Sarno,
- Federico Maria Mongardini,
- Antonio Brescia,
- Leonardo Lenisa,
- Massimiliano Mistrangelo,
- Matteo Zuin,
- Marta Mozzon,
- Alessandro Paolo Chiriatti,
- Vincenzo Bottino,
- Antonio Ferronetti,
- Corrado Rispoli,
- Ludovico Carbone,
- Giuseppe Calabrò,
- Antonino Tirrò,
- Domenico de Vito,
- Giovanna Ioia,
- Giovanni Luca Lamanna,
- Lorenzo Asciore,
- Ettore Greco,
- Pierluigi Bianchi,
- Giuseppe D’Oriano,
- Alessandro Stazi,
- Nicola Antonacci,
- Raffaella Marina Di Renzo,
- Gianmario Edoardo Poto,
- Giuseppe Paolo Ferulano,
- Antonio Longo,
- Ludovico Docimo
Affiliations
- Antonio Brillantino
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Adolfo Renzi
- Esophageal Diseases Center and GERD Unit, Buon Consiglio Hospital, Naples, Italy
- Pasquale Talento
- Department of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy
- Luigi Brusciano
- Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy
- Luigi Marano
- Department of Medicine, Academy of Applied Medical and Social Sciences (Akademia Medycznych i Społecznych Nauk Stosowanych, AMiSNS), Elbląg, Poland
- Maurizio Grillo
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Mauro Natale Maglio
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Fabrizio Foroni
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Alessio Palumbo
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Maria Laura Sandoval Sotelo
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Luciano Vicenzo
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Michele Lanza
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Giovanna Frezza
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Massimo Antropoli
- Deparment of Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Claudio Gambardella
- Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy
- Luigi Monaco
- Department of General Surgery, Villa Esther Clinic, Pineta Grande Hospital, Avellino, Italy
- Ilaria Ferrante
- Department of General Surgery, Villa Esther Clinic, Pineta Grande Hospital, Avellino, Italy
- Domenico Izzo
- Department of General and Emergency Surgery, AORN dei Colli/C.T.O. Hospital, Naples, Italy
- Alfredo Giordano
- Department of General and Emergency Surgery, Hospital of Mercato San Severino, University of Salerno, Salerno, Italy
- Michele Pinto
- Humanitas Castelli, Bergamo, Italy
- Corrado Fantini
- Department of Surgery, Pellegrini Hospital, ASL Napoli 1, Naples, Italy
- Marcello Gasparrini
- Oncologic Colorectal Unit, Sant’Andrea University Hospital, Rome, Italy
- Michele Schiano Di Visconte
- Colorectal and Pelvic Floor Diseases Center, Santa Maria Dei Battuti Hospital, Conegliano (TV) Italy
- Francesca Milazzo
- Department of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy
- Giovanni Ferreri
- Department of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy
- Andrea Braini
- Department of General Surgery, Azienda Sanitaria Friuli Occidentale (ASFO), Pordenone, Italy
- Umberto Cocozza
- Department of General Surgery, S. Maria degli Angeli Hospital, Bari, Italy
- Massimo Pezzatini
- Department of Surgery, Castelli Hospital, ASL Roma 6, Rome, Italy
- Valeria Gianfreda
- Unit of Colonproctologic and Pelvic Surgery, M.G. Vannini Hospital, Rome, Italy
- Alberto Di Leo
- Department of General and Minimally Invasive Surgery, San Camillo Hospital, Trento, Italy
- Vincenzo Landolfi
- Department of General and Specialist Surgery, AORN S.G. Moscati, Avellino, Italy
- Umberto Favetta
- Unit of Proctology and Pelvic Surgery, Città di Pavia Clinic, Pavia, Italy
- Sergio Agradi
- Humanitas Castelli, Bergamo, Italy
- Giovanni Marino
- Department of General Surgery, Santa Marta e Santa Venera Hospital of Acireale, Catania, Italy
- Massimiliano Varriale
- Department of General and Emergency Surgery, Sandro Pertini Hospital, ASL Roma 2, Rome, Italy
- Massimo Mongardini
- La Sapienza University of Rome, Umberto1 Polyclinic, Rome, Italy
- Claudio Eduardo Fernando Antonio Pagano
- Unit of Proctology and Pelvic Surgery, Città di Pavia Clinic, Pavia, Italy
- Riccardo Brachet Contul
- General Ad Urgent Surgery, U. Parini Regional Hospital, Aosta Valley, Italy
- Nando Gallese
- Unit of Proctologic Surgery, Sant’Antonio Clinic, Cagliari, Italy
- Giampiero Ucchino
- Unit of General Surgery, Maggiore Hospital, Bologna, Italy
- Michele D’Ambra
- Department of General and Oncologic Minimally Invasive Surgery, Federico II University, Naples, Italy
- Roberto Rizzato
- Department of General Surgery, Hospital Conegliano - AULSS 2 Marca Trevigiana, Treviso, Italy
- Giacomo Sarzo
- Department of General Surgery, Sant’Antonio Hospital, University of Padova, Padova, Italy
- Bruno Masci
- Department of Surgery, San Carlo di Nancy Hospital, Rome, Italy
- Francesca Da Pozzo
- Department of Surgery, Santa Maria dei Battuti Hospital, Pordenone, Italy
- Simona Ascanelli
- Department of Surgery, University Hospital of Ferrara, Ferrara, Italy
- Patrizia Liguori
- Department of Surgery, Mater Dei Hospital, Bari, Italy
- Angela Pezzolla
- Department of Surgery, University Aldo Moro, Bari, Italy
- Francesca Iacobellis
- Department of General and Emergency Radiology, Antonio Cardarelli Hospital, Naples, Italy
- Erika Boriani
- Department of Surgery, University of Parma, Parma, Italy
- Eugenio Cudazzo
- Department of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy
- Francesca Babic
- Department of Surgery, Cattinara Hospital ASUGI, Trieste, Italy
- Carmelo Geremia
- Unit of Proctology and Pelvic Surgery, Città di Pavia Clinic, Pavia, Italy
- Alessandro Bussotti
- Department of Surgery, San Carlo di Nancy Hospital, Rome, Italy
- Mario Cicconi
- Department of General Surgery, Sant’Omero-Val Vibrata Hospital, Teramo, Italy
- Antonia Di Sarno
- Esophageal Diseases Center and GERD Unit, Buon Consiglio Hospital, Naples, Italy
- Federico Maria Mongardini
- Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy
- Antonio Brescia
- Department of Oncologic Colorectal Surgery, University Hospital S. Andrea, La Sapienza University, Rome, Italy
- Leonardo Lenisa
- Department of Surgery, Surgery Unit, Pelvic Floor Centre, Humanitas San Pio X, Milano, Italy
- Massimiliano Mistrangelo
- Department of Surgery, Le Molinette Hospital, Torino, Italy
- Matteo Zuin
- Unit of General Surgery, Hospital of Cittadella - ULSS 6 Euganea, Padova, Italy
- Marta Mozzon
- Unit of General Surgery, S. Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy
- Alessandro Paolo Chiriatti
- Unit of Surgery, San Francesco Clinic, Galatina, Lecce, Italy
- Vincenzo Bottino
- Unit of Surgery, Betania Evangelical Hospital, Naples, Italy
- Antonio Ferronetti
- Unit of Surgery, Betania Evangelical Hospital, Naples, Italy
- Corrado Rispoli
- Unit of General Surgery, AORN dei Colli/Monaldi Hospital, Naples, Italy
- Ludovico Carbone
- Italian Registry of Physicians and Surgeons, Avellino, Italy
- Giuseppe Calabrò
- Unit of Colonproctology, Euromedica Scientific Institut, Milano, Italy
- Antonino Tirrò
- Unit of Surgery, Santa Marta e Santa Venera Hospital - ASP Catania, Catania, Italy
- Domenico de Vito
- Unit of Surgery, Sanatrix Clinic, Pineta Grande Hospital, Naples, Italy
- Giovanna Ioia
- Department of General and Onologic Surgery, Andrea Tortora Hospital, Pagani, ASL Salerno, Salerno, Italy
- Giovanni Luca Lamanna
- Department of Surgery, A. Moscati Hospital, ASL CE, Aversa, Italy
- Lorenzo Asciore
- Department of Surgery, Ave Gratia Plena Hospital, ALS CE, Caserta, Italy
- Ettore Greco
- Department of Surgery, P. Colombo Hospital, Rome, Italy
- Pierluigi Bianchi
- Department of Surgery, P. Colombo Hospital, Rome, Italy
- Giuseppe D’Oriano
- Department of Surgery, San Paolo Hospital, ALS NA 1, Naples, Italy
- Alessandro Stazi
- Unit of Surgery, Madonna delle Grazie Clinic, Rome, Italy
- Nicola Antonacci
- Week Surgery and Day Surgery Unit, AUSL Romagna Bufalini Hospital, Cesena, Italy
- Raffaella Marina Di Renzo
- Department of General and Oncological Surgery, Pierangeli Clinic, Pescara, Italy
- Gianmario Edoardo Poto
- Italian Registry of Physicians and Surgeons, Avellino, Italy
- Giuseppe Paolo Ferulano
- Department of Surgery, Federico II University, Naples, Italy
- Antonio Longo
- Department of Surgery, Madonna della Fiducia Clinic, Rome, Italy
- Ludovico Docimo
- Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy
- DOI
- https://doi.org/10.3393/ac.2023.00871.0124
- Journal volume & issue
-
Vol. 40,
no. 4
pp. 287 – 320
Abstract
The aim of these evidence-based guidelines is to present a consensus position from members of the Italian Unitary Society of Colon-Proctology (Società Italiana Unitaria di Colon-Proctologia, SIUCP) on the diagnosis and management of hemorrhoidal disease, with the goal of guiding physicians in the choice of the best treatment option. A panel of experts was charged by the Board of the SIUCP to develop key questions on the main topics related to the management of hemorrhoidal disease and to perform an accurate and comprehensive literature search on each topic, in order to provide evidence-based answers to the questions and to summarize them in statements. All the clinical questions were discussed by the expert panel in multiple rounds through the Delphi approach and, for each statement, a consensus among the experts was reached. The questions were created according to PICO (patients, intervention, comparison, and outcomes) criteria, and the statements were developed adopting the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) methodology. In cases of grade 1 hemorrhoidal prolapse, outpatient procedures including hemorrhoidal laser procedure and sclerotherapy may be considered the preferred surgical options. For grade 2 prolapse, nonexcisional procedures including outpatient treatments, hemorrhoidal artery ligation and mucopexy, laser hemorrhoidoplasty, the Rafaelo procedure, and stapled hemorrhoidopexy may represent the first-line treatment options, whereas excisional surgery may be considered in selected cases. In cases of grades 3 and 4, stapled hemorrhoidopexy and hemorrhoidectomy may represent the most effective procedures, even if, in the expert panel opinion, stapled hemorrhoidopexy represents the gold-standard treatment for grade 3 hemorrhoidal prolapse.
Keywords
- hemorrhoids
- stapled hemorrhoidopexy
- hemorrhoidopexy
- hemorrhoidal artery ligation and mucopexy
- laser hemorrhoidoplasty