Advances in Understanding the Mechanism of Baicalin in Ameliorating Cognitive Dysfunction Associated with Sleep Disorders

Abstract

Baicalin (BA), a flavonoid extracted from the roots of Scutellaria baicalensis, has significant neuroprotective, anti-inflammatory, antioxidant, and anti-apoptotic properties, with a notable safety profile and low negative effects. BA has been acknowledged for its capacity to prevent and cure cognitive deficits and learning impairments linked to illnesses of the central nervous system. Simultaneously, sleep disorders (SD), which often occur along with cognitive dysfunctions, have shown improvement with BA therapy, but the exact reasons behind this improvement are not yet completely understood. This study presents a comprehensive overview of the existing pharmacological knowledge on BA and examines its recent progress in treating cognitive deficits. The goal is to provide fresh insights on how to effectively use BA and traditional Chinese medicine for addressing cognitive dysfunctions.

Keywords

• baicalin
• sleep disorders
• cognitive dys function