BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts

Beibei Wang; Beibei Wang; Huayi Yang; Jianan Sun; Chuhao Dou; Jian Huang; Jian Huang; Feng-Biao Guo; Feng-Biao Guo

doi:10.3389/fmicb.2021.593979

Frontiers in Microbiology (Jan 2021)

BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts

Beibei Wang,
Beibei Wang,
Huayi Yang,
Jianan Sun,
Chuhao Dou,
Jian Huang,
Jian Huang,
Feng-Biao Guo,
Feng-Biao Guo

Affiliations

Beibei Wang: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Beibei Wang: Centre for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China
Huayi Yang: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Jianan Sun: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Chuhao Dou: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Jian Huang: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Jian Huang: Centre for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China
Feng-Biao Guo: School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
Feng-Biao Guo: Centre for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China

DOI: https://doi.org/10.3389/fmicb.2021.593979
Journal volume & issue: Vol. 12

Abstract

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Synthetic biology seeks to create new biological parts, devices, and systems, and to reconfigure existing natural biological systems for custom-designed purposes. The standardized BioBrick parts are the foundation of synthetic biology. The incomplete and flawed metadata of BioBrick parts, however, are a major obstacle for designing genetic circuit easily, quickly, and accurately. Here, a database termed BioMaster http://www.biomaster-uestc.cn was developed to extensively complement information about BioBrick parts, which includes 47,934 items of BioBrick parts from the international Genetically Engineered Machine (iGEM) Registry with more comprehensive information integrated from 10 databases, providing corresponding information about functions, activities, interactions, and related literature. Moreover, BioMaster is also a user-friendly platform for retrieval and analyses of relevant information on BioBrick parts.

Published in Frontiers in Microbiology

ISSN: 1664-302X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/journals/microbiology

About the journal

Abstract

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