Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer

Zheng Han; Xiaohui Wu; Sarah Roelle; Chuheng Chen; William P. Schiemann; Zheng-Rong Lu

doi:10.1038/s41467-017-00741-y

Nature Communications (Sep 2017)

Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer

Zheng Han,
Xiaohui Wu,
Sarah Roelle,
Chuheng Chen,
William P. Schiemann,
Zheng-Rong Lu

Affiliations

Zheng Han: Case Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University
Xiaohui Wu: Case Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University
Sarah Roelle: Case Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University
Chuheng Chen: Case Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University
William P. Schiemann: Case Comprehensive Cancer Center, Case Western Reserve University
Zheng-Rong Lu: Case Center for Biomolecular Engineering, Department of Biomedical Engineering, Case Western Reserve University

DOI: https://doi.org/10.1038/s41467-017-00741-y
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 9

Abstract

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Molecular MRI is a powerful clinical tool for non-invasive detection of cancer biomarkers. Here, the authors develop a targeted peptide gadofullerene contrast agent that can sensitively distinguish between breast cancers of different aggressiveness.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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