Nature Communications (Sep 2022)

The augmin complex architecture reveals structural insights into microtubule branching

  • Erik Zupa,
  • Martin Würtz,
  • Annett Neuner,
  • Thomas Hoffmann,
  • Mandy Rettel,
  • Anna Böhler,
  • Bram J. A. Vermeulen,
  • Sebastian Eustermann,
  • Elmar Schiebel,
  • Stefan Pfeffer

DOI
https://doi.org/10.1038/s41467-022-33228-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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The formation of branched microtubule networks in mitotic spindles depends on the augmin complex. Zupa, Würtz et al. elucidate the molecular architecture and conformational plasticity of the augmin complex using integrative structural biology, providing structural insights into microtubule branching.