Thermal degradation of pesticide active substances: Prioritisation list

Abstract

This study aims at estimating which pesticide active substances (ASs) are the best candidates to study potential further degradation of the AS above 120°C. To achieve this, a prioritisation list was built following five consecutive criteria. This first includes substances that are anthropogenic, have a carbon backbone structure, are authorized in the European Union, and have a defined maximum residue limit (MRL). Then, substances were selected according to their physicochemical and structural properties, MRL in main food commodities, standard price and degradation in hydrolysis studies below 120°C. The results showed that out of the initial 1 478 substances reported in the European pesticide database, 24 ASs were selected as the best candidates to test the assumption of degradation above 120°C. This prioritisation list could be useful for future research studies to build their own list and save time in selecting suitable candidates according to their criteria.

Keywords

• Prioritisation workflow
• active substance
• pesticides
• thermal degradation
• hydrolysis