Synthesis of a New Series of 4H-benzo[h]chromenes by a Multicomponent Reaction under Solvent-Free Microwave Conditions

Abstract

Multicomponent condensation of 1-naphthol, malononitrile, and arylglyoxals in the presence of Mg-Al hydrotalcite under solvent-free MicroWave (MW) conditions gave a new series of 2-amino-4-aroyl-4H-benzo[h]chromene-3-carbonitriles in high yields (70-89%). The structure of all products was elucidated by their FT-IR, 1H-NMR, 13C-NMR spectral data and microanalysis.

Keywords

• arylglyoxals
• 1-naphthol
• malononitrile
• mg-al hydrotalcite
• 4h-benzo[h]chromenes
• microwaves
• multicomponent reaction