Memorias do Instituto Oswaldo Cruz (Jan 1987)

Methionine enkephalin: immunomodulator in normal volunteers, cancer and AIDS patients

  • Nicholas P. Plotnikoff,
  • Gerald C. Miller,
  • Nadim F. Nimeh,
  • Joseph Wybran

DOI
https://doi.org/10.1590/S0074-02761987000600011
Journal volume & issue
Vol. 82
pp. 67 – 73

Abstract

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Clinical studies of the immunological effects of methionine enkephalin in normal volunteers, cancer, and AIDS patients are summarized. The major immunology changes seen were increases in T cell subsets, natural killer activity, as well as mitogen blastogenesis. Clinically, the cancer and ARC patients did not develop infections.