Investigation of the recrystallization process of vaterite microparticles containing magnetite nanoparticles grown on polycaprolactone fibers by ultrasonic treatment

Abstract

Background and Objectives. A method for mineralizing polycaprolactone nanofibers by calcium carbonate (vaterite) microparticles containing nanoparticles of mixed iron oxide (magnetite) using the ultrasonic treatment is proposed. Materials and Methods: The process of recrystallization vaterite microparticles, which are part of the composite material, into calcite using X-ray diffraction and scanning electron microscopy was studied. Results: The resulting composite material can be used in tissue engineering as either a scaffold for cell growth or a drug carrier for their local release. Conclusion: It has been found that the complete process of recrystallization of vaterite into calcite takes about 27 hours, while the recrystallization rate increases significantly after 12 hours of exposure to water. According to X-ray diffraction data, there are no magnetic nanoparticles in the resulting coating by 24 o’clock. This is due to their gradual release as a result of the recrystallization of vaterite into calcite.

Keywords

• calcium carbonate microparticles
• magnetite nanoparticles
• polycaprolactone nanofibers
• regenerative medicine