Frontiers in Pharmacology (Feb 2024)

Leniolisib: a novel treatment for activated phosphoinositide-3 kinase delta syndrome

Surya K. De,
Surya K. De

Affiliations

Surya K. De: Conju-Probe, San Diego, CA, United States
Surya K. De: Bharath University, Department of Chemistry, Chennai, Tamil Nadu, India

DOI: https://doi.org/10.3389/fphar.2024.1337436
Journal volume & issue: Vol. 15

Abstract

Graphical AbstractIC50 = 11 nM (PI3Kδ); 244 nM (PI3Kα); 424 nM (PI3Kβ), 2,230 nM (PI3Kγ).

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

About the journal