Skin Health and Disease (Apr 2024)

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

  • Chandni Patel,
  • Barbara De Barros,
  • Stephen L. Walker

DOI
https://doi.org/10.1002/ski2.339
Journal volume & issue
Vol. 4, no. 2
pp. n/a – n/a

Abstract

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Abstract Leprosy is caused by Mycobacterium leprae. The condition primarily affects the skin and peripheral nerves. There are two types of leprosy reactions, Type 1 and Type 2 or erythema nodosum leprosum (ENL). ENL is a severe multi‐system, immune‐mediated complication of lepromatous leprosy. It is characterised by widespread painful cutaneous nodules, fever and peripheral oedema. This report discusses the unusual case of a 29‐year‐old woman who developed a localised form of ENL which required thalidomide to induce remission.