Nature Communications (Jul 2016)

Hypoxia causes transgenerational impairments in reproduction of fish

  • Simon Yuan Wang,
  • Karen Lau,
  • Keng-Po Lai,
  • Jiang-Wen Zhang,
  • Anna Chung-Kwan Tse,
  • Jing-Woei Li,
  • Yin Tong,
  • Ting-Fung Chan,
  • Chris Kong-Chu Wong,
  • Jill Man-Ying Chiu,
  • Doris Wai-Ting Au,
  • Alice Sze-Tsai Wong,
  • Richard Yuen-Chong Kong,
  • Rudolf Shiu-Sun Wu

DOI
https://doi.org/10.1038/ncomms12114
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 9

Abstract

Read online

Hypoxia has diverse effects on aquatic life. Wang et al.show that reproductive defects resulting from hypoxia are epigenetically heritable in Japanese rice fish, and that this intergenerational inheritance is accompanied by differential methylation and gene expression in sperm.