Steroidal antiinflammatory drugs: glucocorticoids

Abstract

Glucocorticoids are largely used drugs because of theirimmunosuppressive and anti-infl ammatory effects in the treatment ofmany rheumatic and other infl ammatory diseases. However, their useis sometimes limited by numerous adverse reactions. In this chapterphysiologic and pharmacological aspects as well as their mechanismof action and administration are presented. The use of glucocorticoidsin old age is specially discussed. Drug interaction and adverse effectsare also reviewed.

Keywords

• Adrenal cortex hormones
• Anti-infl ammatory agents