EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS

Abstract

BACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acid­forming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients with chemical burns of the stomach grade III­IV who had underwent standard therapy. The complex therapy for 20 patients included 5 days of intravenous Rabeloc, 20 mg daily.RESULTS. Rabeloc included into the complex of therapeutic measures in patients with chemical burns of the stomach grade III–IV helped reduce the length of stay in the ICU by 1.5 times and inpatient treatment by 1.8 times, reduce the frequency of early secondary hemorrhage and decompensated cicatricial narrowing of the stomach.CONCLUSION. Early parenteral use of Rabeloc increases the effectiveness of complex therapy for acute poisoning with cauterant substances.

Keywords

• chemical burn of the stomach
• proton pump inhibitors