Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent

Wang Liang; Zhu Kai-Qiang; Chen Qun; He Ming-Yang

doi:10.1515/gps-2014-0056

Green Processing and Synthesis (Dec 2014)

Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent

Wang Liang,
Zhu Kai-Qiang,
Chen Qun,
He Ming-Yang

Affiliations

Wang Liang: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of China
Zhu Kai-Qiang: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of China
Chen Qun: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of China
He Ming-Yang: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of China

DOI: https://doi.org/10.1515/gps-2014-0056
Journal volume & issue: Vol. 3, no. 6
pp. 457 – 461

Abstract

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An efficient one-pot synthesis of polyhydroacridines and polyhydroquinolines through the Hantzsch reaction in deep eutectic solvent choline chloride/urea (1:2) has been developed. Good to excellent yields, broad substrate compatibility as well as the reusability of the solvent are the major advantages of the present protocol.

Published in Green Processing and Synthesis

ISSN: 2191-9542 (Print); 2191-9550 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry
Website: https://www.degruyter.com/view/j/gps

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