Nature Communications (Feb 2019)

Correspondence between cerebral glucose metabolism and BOLD reveals relative power and cost in human brain

  • Ehsan Shokri-Kojori,
  • Dardo Tomasi,
  • Babak Alipanahi,
  • Corinde E. Wiers,
  • Gene-Jack Wang,
  • Nora D. Volkow

DOI
https://doi.org/10.1038/s41467-019-08546-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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The brain primarily uses glucose to generate energy, but the relationship of neuronal activity to glucose utilization is not necessarily a simple linear one. Here, the authors introduce relative power (rPWR) and relative cost (rCST) as new metrics to quantify how brain activity relates to glucose consumption.