Phytosynthesized Metallic Nanoparticles—between Nanomedicine and Toxicology. A Brief Review of 2019′s Findings
Irina Fierascu,
Ioana Catalina Fierascu,
Roxana Ioana Brazdis,
Anda Maria Baroi,
Toma Fistos,
Radu Claudiu Fierascu
Affiliations
Irina Fierascu
National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM Bucharest, Emerging Nanotechnologies Group, 202 Spl. Independentei, 060021 Bucharest, Romania
Ioana Catalina Fierascu
University of Medicine and Pharmacy “Carol Davila”, 37 Dionisie Lupu Str., 030167 Bucharest, Romania
Roxana Ioana Brazdis
National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM Bucharest, Emerging Nanotechnologies Group, 202 Spl. Independentei, 060021 Bucharest, Romania
Anda Maria Baroi
National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM Bucharest, Emerging Nanotechnologies Group, 202 Spl. Independentei, 060021 Bucharest, Romania
Toma Fistos
National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM Bucharest, Emerging Nanotechnologies Group, 202 Spl. Independentei, 060021 Bucharest, Romania
Radu Claudiu Fierascu
National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM Bucharest, Emerging Nanotechnologies Group, 202 Spl. Independentei, 060021 Bucharest, Romania
Phytosynthesized nanoparticles represent a continuously increasing field of research, with numerous studies published each year. However, with the emerging interest in this area, the quality of the published works is also continuously increasing, switching from routine antioxidant or antimicrobial studies on trivial microbial lines to antibiotic-resistant strains or antitumoral studies. However, this increasing interest has not been not reflected in the studies regarding the toxicological effects of nanoparticles (NPs); this should be a subject of greatest interest, as the increasing administration of NPs in general (and phytosynthesized NPs in particular) could lead to their accumulation in the environment (soil, water and living organisms). The present review aims to present the most recent findings in the application of phytosynthesized NPs as antimicrobial and antitumoral agents, as well as the results regarding their toxicological potential.
