EVALUATION OF PROHYPERTENSIVE EFFECT OF MELOXICAM ON THE BLOOD PRESSURE INDICATORS

Abstract

The goal is to evaluate the influence of meloxicam on the level of blood pressure among patients suffering from hypertension, as well as among patients without diseases of the cardiovascular system, in relation to its pro-hypertensive effect.Materials and methods. The retrospective research involved 60 patients who regularly taked meloxicam in a dose of 7.5 mg / day. There were patients who didn’t have a cardiovascular pathology in the first group. The second group consisted of patients with hypertension, taking antihypertensive drugs. Retrospectively, the level of blood pressure, measured by the Korotkov’s method, was analyzed by medical histories, before and after 3 months of taking meloxicam in both groups. The total cardiovascular risk was calculated on a SCORE scale.Results. It was determinated that long-term medication of meloxicam led to an increase of blood pressure indicators, both in patients without established diseases of the cardiovascular system, and in patients with the hypertension and an average total cardiovascular risk, who are regularly taking antihypertensive pills to achieve target blood pressure.

Keywords

• meloxicam
• nsaids
• blood pressure
• arterial hypertension
• pro-hypertensive effect
• hypotensive therapy