Measles, mumps, rubella vaccination experience in infants with egg allergy

Abstract

Aim: Food allergy prevelance is increasing in the childhood. Egg allergy isth e second most common allergen after the milk. Measles, mumps, rubella (MMR) vaccines can contain trace amount of egg protein due to the live virus produced in the chick embryo cultures. So it could be some concerns about vaccination of egg allergic infants. In our study, we aim to evaluate the side effects of egg allergic infants after MMR vaccination that applied to 12 months olds.Material and Methods: Fourty four egg allergic patients who were following up and vaccinated on the 12 months between February 2018 and April 2019 enrolled in the study. Demographic features, clinical diagnoses, skin prick tests, spesific IgE tests, eosinophils, total IgE levels from evaluated patients and side effects after vaccination were evaulated retrospectively.Results: Twenty four (54,5%) patients were female, 20 (45,5%) patients were male. Thirthy one (70,4%) patients had atopic dermatitis, 7 (15,9%) patients had urticaria/rash, 6 (13,6%) patients had reactive airways disease. In the skin prick tests 31 (70,5%) patients had sensitivity to egg whites, 26 (59,1%) patients had sensivity to egg yolk. Four (9%) of 44 patients from vaccinated with MMR had side effects. Reactions had been observed in the first 4 hours in 3 patients and in 24 hours in one patient. There was no severe side effect in any patients.Conclusion: Considering the importance of immunization, MMR vaccine could ap-ply safely in egg allergic patients due to very low anaphylaxis risk. But we think that the vaccine should be made with emergency aid conditions in atopic children and they should be kept in proper time.

Keywords

• egg allergy
• measles mumps rubella vaccines
• infant
• yumurta alerjisi
• kızamık kızamıkçık kabakulak aşısı
• süt çocuğu