Nature Communications (Jan 2018)
The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2
Abstract
LncRNAs influence endothelial cell function via a number of mechanisms. Here the authors show that the lncRNA GATA6-AS regulates endothelial gene expression through interaction with the nuclear deaminase LOXL2, with functional consequences on endothelial-mesenchymal transition and angiogenesis.