Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

Karamitrousis E.; Balgkouranidou I.; Xenidis N.; Amarantidis K.; Biziota E.; Koukaki T.; Kakolyris S.

doi:10.2478/fco-2021-0010

Forum of Clinical Oncology (May 2022)

Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

Karamitrousis E.,
Balgkouranidou I.,
Xenidis N.,
Amarantidis K.,
Biziota E.,
Koukaki T.,
Kakolyris S.

Affiliations

Karamitrousis E.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Balgkouranidou I.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Xenidis N.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Amarantidis K.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Biziota E.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Koukaki T.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece
Kakolyris S.: University Medical Oncology Department, Medical School, Democritus University of Thrace, Alexandroupolis, 68100, Greece

DOI: https://doi.org/10.2478/fco-2021-0010
Journal volume & issue: Vol. 12, no. 3
pp. 72 – 76

Abstract

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Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.

Published in Forum of Clinical Oncology

ISSN: 1792-362X (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://sciendo.com/journal/FCO

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