The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (Sep 2024)

Vertebral artery dissection from etiopathogenesis to management therapy: a narrative review with neuroimaging’s case illustration

  • Muhammad Yunus Amran,
  • Irbab Hawari,
  • Fitri Jafani La’biran,
  • Siti Giranti Ardilia Gunadi,
  • Lisa Tenriesa Muslich

DOI
https://doi.org/10.1186/s41983-024-00893-x
Journal volume & issue
Vol. 60, no. 1
pp. 1 – 9

Abstract

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Abstract Vertebral artery dissection is one of the causes of stroke and transient ischemic attack in young adults, with an incidence rate of 1.0–1.1 per 100,000 people. Vertebral artery dissection occurs due to a tear in the vertebral artery wall, which results in blood flow entering the blood vessel wall. The etiology of vertebral artery dissection is very diverse, which can be classified as intrinsic (such as anatomical abnormalities of the blood vessels) or extrinsic (such as trauma), and there are several rarer causes. The most frequent clinical manifestations include stroke, transient ischemic attack, neck pain, headaches, and vertigo. Management in this case comprises treatment according to symptoms in the form of intravenous thrombolysis, administering antithrombotic drugs, and endovascular therapy.

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