Nature Communications (Sep 2022)
Insular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways
- Qi Wang,
- Jia-Jie Zhu,
- Lizhao Wang,
- Yan-Peng Kan,
- Yan-Mei Liu,
- Yan-Jiao Wu,
- Xue Gu,
- Xin Yi,
- Ze-Jie Lin,
- Qin Wang,
- Jian-Fei Lu,
- Qin Jiang,
- Ying Li,
- Ming-Gang Liu,
- Nan-Jie Xu,
- Michael X. Zhu,
- Lu-Yang Wang,
- Siyu Zhang,
- Wei-Guang Li,
- Tian-Le Xu
Affiliations
- Qi Wang
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Jia-Jie Zhu
- Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine
- Lizhao Wang
- Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine
- Yan-Peng Kan
- Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine
- Yan-Mei Liu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Yan-Jiao Wu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Xue Gu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Xin Yi
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Ze-Jie Lin
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Qin Wang
- Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine
- Jian-Fei Lu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Qin Jiang
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Ying Li
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Ming-Gang Liu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Nan-Jie Xu
- Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine
- Michael X. Zhu
- Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston
- Lu-Yang Wang
- Program in Neuroscience and Mental Health, SickKids Research Institute
- Siyu Zhang
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Wei-Guang Li
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- Tian-Le Xu
- Center for Brain Science, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-33241-9
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
Ensembles of fear and extinction memories compete and interact to drive opposing behaviors. Here the authors identified insular cortical circuits as an executive gateway that decipher between fear and extinction memories via distinct subcortical pathways.
