Interleukin-6 kinetics can be useful for early treatment monitoring of severe bacterial sepsis and septic shock

Abstract

Early appropriate anti-microbial therapy is necessary to improve outcomes of septic patients. We describe 20 case histories of patients with severe bacterial sepsis regarding kinetics of several biomarkers. We found that interleukin-6 is able to predict survival and might be able to evaluate appropriateness of anti-microbial therapy.

Keywords

• Interleukin-6
• C reactive protein
• procalcitonin
• bacterial sepsis
• monitoring