Nature Communications (Sep 2021)
Brown adipose tissue monocytes support tissue expansion
- Alexandre Gallerand,
- Marion I. Stunault,
- Johanna Merlin,
- Hannah P. Luehmann,
- Deborah H. Sultan,
- Maria M. Firulyova,
- Virginie Magnone,
- Narges Khedher,
- Antoine Jalil,
- Bastien Dolfi,
- Alexia Castiglione,
- Adelie Dumont,
- Marion Ayrault,
- Nathalie Vaillant,
- Jérôme Gilleron,
- Pascal Barbry,
- David Dombrowicz,
- Matthias Mack,
- David Masson,
- Thomas Bertero,
- Burkhard Becher,
- Jesse W. Williams,
- Konstantin Zaitsev,
- Yongjian Liu,
- Rodolphe R. Guinamard,
- Laurent Yvan-Charvet,
- Stoyan Ivanov
Affiliations
- Alexandre Gallerand
- Université Côte d’Azur, INSERM, C3M
- Marion I. Stunault
- Université Côte d’Azur, INSERM, C3M
- Johanna Merlin
- Université Côte d’Azur, INSERM, C3M
- Hannah P. Luehmann
- Department of Radiology, Washington University School of Medicine
- Deborah H. Sultan
- Department of Radiology, Washington University School of Medicine
- Maria M. Firulyova
- Computer Technologies Department, ITMO University
- Virginie Magnone
- Université Côte d’Azur, CNRS, IPMC
- Narges Khedher
- Université Côte d’Azur, INSERM, C3M
- Antoine Jalil
- Université Bourgogne Franche-Comté, LNC UMR1231
- Bastien Dolfi
- Université Côte d’Azur, INSERM, C3M
- Alexia Castiglione
- Université Côte d’Azur, INSERM, C3M
- Adelie Dumont
- Université Côte d’Azur, INSERM, C3M
- Marion Ayrault
- Université Côte d’Azur, INSERM, C3M
- Nathalie Vaillant
- Université Côte d’Azur, INSERM, C3M
- Jérôme Gilleron
- Université Côte d’Azur, INSERM, C3M
- Pascal Barbry
- Université Côte d’Azur, CNRS, IPMC
- David Dombrowicz
- Univ.Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID
- Matthias Mack
- Department of Internal Medicine - Nephrology, University Hospital Regensburg
- David Masson
- Université Bourgogne Franche-Comté, LNC UMR1231
- Thomas Bertero
- Université Côte d’Azur, CNRS, IPMC
- Burkhard Becher
- Institute of Experimental Immunology, University of Zürich
- Jesse W. Williams
- Department of Integrative Biology and Physiology, Center for Immunology, University of Minnesota Medical School
- Konstantin Zaitsev
- Computer Technologies Department, ITMO University
- Yongjian Liu
- Department of Radiology, Washington University School of Medicine
- Rodolphe R. Guinamard
- Université Côte d’Azur, INSERM, C3M
- Laurent Yvan-Charvet
- Université Côte d’Azur, INSERM, C3M
- Stoyan Ivanov
- Université Côte d’Azur, INSERM, C3M
- DOI
- https://doi.org/10.1038/s41467-021-25616-1
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 13
Abstract
Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and show that monocytes contribute to brown adipose tissue expansion.
