Quality analysis of fresh frozen plasma prepared by the improved ultra-low temperature storage box

Abstract

Objective To observe and analyze the influence of the improved ultra-low temperature storage box on the quality of fresh frozen plasma (FFP). Methods A total of 80 qualified whole blood samples (400 mL, O type not included) collected from July to November in 2023 were selected, and were divided into 4 groups, with 20 samples in each group. Group A: quick-frozen in a traditional low temperature box for 1 hour and then stored in a -30℃ cold storage; Group B: quick-frozen in the flat freezer for 1 hour and then stored in a -30℃ cold storage; Group C: quick-frozen in a newly improved ultra-low temperature storage box for 1 hour and stored in a -30℃ cold storage; Group D: quick-frozen in a new improved ultra-low temperature storage box for 12 hours and stored in a -30℃ cold storage. The contents of FⅧ and fibrinogen (Fg) in four groups were detected. Results The contents of FⅧ in group B, C and D were significantly higher than those in group A, with statistical difference (P0.05), and no statistical difference in the contents of Fg was found among the four groups(P>0.05). Conclusion The improved ultra-low temperature storage box is superior to the traditional low temperature box in preparing FFP, and there is no obvious difference between the improved ultra-low temperature storage box and the flat-plate quick freezer. However, the improved ultra-low temperature storage box can make the process of preparing FFP more flexible and improve the efficiency of component preparation.

Keywords

• fresh frozen plasma
• fⅷ
• ultra-low temperature storage box