We describe comparatively cryogenically cooled Tm, Ho: GdVO4 lasers with an emission wavelength of 2.05 μm under continuous wave and pulse operating mode. By varying the transmittance of output couplers to be 0.40 for a continuous wave laser, the maximum output power of 7.4 W was generated with a slope efficiency of 43.3% when the absorbed pump power was increased to 18.7 W. For passively Q-switched lasers, the output characteristics were researched through altering pump mode radius. When the pump mode radius focused into the Tm, Ho: GdVO4 center equaled near 600 μm, the peak power was increased to be the maximum value of 9.9 kW at the absorbed pump power of 11.8 W. The pulse energy of 0.39 mJ was achieved at the same absorbed pump power with repetition of 5.7 kHz.
