Translational Neuroscience (Oct 2023)
Cdk5 activation promotes Cos-7 cells transition towards neuronal-like cells
Abstract
Cyclin-dependent kinase 5 (Cdk5) activity is specifically active in neurogenesis, and Cdk5 and neocortical neurons migration related biomarker are expressed in Cos-7 cells. However, the function of Cdk5 on the transformation of immortalized Cos-7 cells into neuronal-like cells is not clear.
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