Pneumocystis jirovecii pneumonia in a X-linked chronic granulomatous disease female carrier
Vasiliki Kalotychou,
Demetrios Mermigkis,
Maria G. Kanariou,
Marianna Tzanoudaki,
Vasiliki Epameinondas Georgakopoulou,
Irene Kourbeti,
George L. Daikos
Affiliations
Vasiliki Kalotychou
First Department of Medicine, National and Kapodistrian University of Athens, Laikon, General Hospital, Greece
Demetrios Mermigkis
First Pulmonary Department, Sismanogleio General Hospital, Athens, Greece
Maria G. Kanariou
Department of Immunology-Histocompatibility, Specialized Center & Referral Center for Primary Immunodeficiencies-Paediatric Immunology, ''Aghia Sophia'' Children's Hospital, Athens, Greece
Marianna Tzanoudaki
Department of Immunology-Histocompatibility, Specialized Center & Referral Center for Primary Immunodeficiencies-Paediatric Immunology, ''Aghia Sophia'' Children's Hospital, Athens, Greece
Vasiliki Epameinondas Georgakopoulou
First Pulmonary Department, Sismanogleio General Hospital, Athens, Greece
Irene Kourbeti
First Department of Medicine, National and Kapodistrian University of Athens, Laikon, General Hospital, Greece
George L. Daikos
First Department of Medicine, National and Kapodistrian University of Athens, Laikon, General Hospital, Greece; Correspondence to: First Department of Medicine, National and Kapodistrian University of Athens, Laikon General Hospital, Mikras Asias 75, Athens 11527, Greece.
The X-chromosome linked (XL) female carriers of chronic granulomatous disease (CGD) are considered to have no risk for infection. Herein we present a female CGD XL-carrier who developed Pneumocystis jirovecii pneumonia and Serratia marcescens infection associated with age-related skewing of X-chromosome inactivation.
